It's another of those vague ideas that has fascinated - and frustrated - me throughout most of my life. In long run, I'd like it to become one of the underlying grand themes of this place. I also don't have a clue how to begin tackling it. So instead I'll throw in another of my favourite Ted videos that takes a peek into a similar matter.
Also, this recent post from IO9 about how science works and how it doesn't tickles the same nerve [<<- metaphor, duh].